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1

The WNT signaling pathways in wound healing and fibrosis

Burgy, Olivier, Königshoff, Melanie

Journal:

Year:

2018

Language:

english

File:

PDF, 2.43 MB

english, 2018

2

Shared and distinct mechanisms of fibrosis

Distler, Jörg H. W., Györfi, Andrea-Hermina, Ramanujam, Meera, Whitfield, Michael L., Königshoff, Melanie, Lafyatis, Robert

Journal:

Nature Reviews Rheumatology (formerly Nature Clinical Practice Rheumatology)

Year:

2019

File:

PDF, 2.29 MB

2019

3

Dynamic expression of HOPX in alveolar epithelial cells reflects injury and repair during the progression of pulmonary fibrosis

Ota, Chiharu, Ng-Blichfeldt, John-Poul, Korfei, Martina, Alsafadi, Hani N., Lehmann, Mareike, Skronska-Wasek, Wioletta, M. De Santis, Martina, Guenther, Andreas, Wagner, Darcy E., Königshoff, Melanie

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 8.47 MB

english, 2018

4

Protease-Mediated Release of Chemotherapeutics from Mesoporous Silica Nanoparticles to ex Vivo Human and Mouse Lung Tumors

van Rijt, Sabine H., Bölükbas, Deniz A., Argyo, Christian, Datz, Stefan, Lindner, Michael, Eickelberg, Oliver, Königshoff, Melanie, Bein, Thomas, Meiners, Silke

Journal:

Year:

2015

Language:

english

File:

PDF, 988 KB

english, 2015

5

Pulmonary CCR2 + CD4 + T cells are immune regulatory and attenuate lung fibrosis development

Milger, Katrin, Yu, Yingyan, Brudy, Eva, Irmler, Martin, Skapenko, Alla, Mayinger, Michael, Lehmann, Mareike, Beckers, Johannes, Reichenberger, Frank, Behr, Jürgen, Eickelberg, Oliver, Königshoff, Mel

Journal:

Year:

2017

Language:

english

File:

PDF, 9.02 MB

english, 2017

6

Age-Dependent Decline in Mouse Lung Regeneration with Loss of Lung Fibroblast Clonogenicity and Increased Myofibroblastic Differentiation

Paxson, Julia A., Gruntman, Alisha, Parkin, Christopher D., Mazan, Melissa R., Davis, Airiel, Ingenito, Edward P., Hoffman, Andrew M., Königshoff, Melanie

Journal:

Year:

2011

Language:

english

File:

PDF, 2.46 MB

english, 2011

7

Canonical Wnt Signaling Activity in Early Stages of Chick Lung Development

Moura, Rute Silva, Carvalho-Correia, Eduarda, daMota, Paulo, Correia-Pinto, Jorge, Königshoff, Melanie

Journal:

Year:

2014

Language:

english

File:

PDF, 43.33 MB

english, 2014

8

Cigarette smoke extract affects mitochondrial function in alveolar epithelial cells

Ballweg, K., Mutze, K., Konigshoff, M., Eickelberg, O., Meiners, S.

Journal:

AJP Lung Cellular and Molecular Physiology

Year:

2014

Language:

english

File:

PDF, 1.75 MB

english, 2014

9

HER-2/neu Gene Copy Number Quantified by Real-Time PCR: Comparison of Gene Amplification, Heterozygosity, and Immunohistochemical Status in Breast Cancer Tissue

Journal:

Clinical Chemistry

Year:

2003

Language:

english

File:

PDF, 280 KB

english, 2003

10

Immune system dysregulation in chronic lung disease

Marsland, B. J., Konigshoff, M., Saglani, S., Eickelberg, O.

Journal:

European Respiratory Journal

Year:

2011

Language:

english

File:

PDF, 212 KB

english, 2011

11

[American Thoracic Society American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans - ()] B28. OXIDATIVE STRESS, SIGNAL TRANSDUCTION AND MECHANISMS OF LUNG INJURY - Microarray Analysis Reveals NFIB As A Potential Target Of The Matricellular Protein WISP1 In Alveolar Epithelial Cells In Idiopathic Pulmonary Fibrosis

Konigshoff, Melanie, Rensing, Nele, Wilhelm, Jochen, Balsara, Nisha, Eickelberg, Oliver

Year:

2010

Language:

english

File:

PDF, 18 KB

english, 2010

12

[American Thoracic Society American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans - ()] C61. GENE REGULATION DURING DEVELOPMENT AND IN INJURY - Expression Profiling Of Protein Arginine Methyltransferase (Prmt) Isoforms In Chronic Obstructive Pulmonary Disease (COPD)

Yildirim, Ali O., Konigshoff, Melanie, Wang, Qiongman, Eickelberg, Oliver

Year:

2010

Language:

english

File:

PDF, 16 KB

english, 2010

13

Retinoic acid signaling balances adult distal lung epithelial progenitor cell growth and differentiation

Ng-Blichfeldt, John-Poul, Schrik, Anneke, Kortekaas, Rosa K., Noordhoek, Jacobien A., Heijink, Irene H., Hiemstra, Pieter S., Stolk, Jan, Königshoff, Melanie, Gosens, Reinoud

Journal:

Year:

2018

Language:

english

File:

PDF, 4.23 MB

english, 2018

14

Lung ageing and COPD: is there a role for ageing in abnormal tissue repair?

Brandsma, Corry-Anke, de Vries, Maaike, Costa, Rita, Woldhuis, Roy R., Königshoff, Melanie, Timens, Wim

Journal:

European Respiratory Review

Year:

2017

Language:

english

File:

PDF, 580 KB

english, 2017

15

The WNT signaling pathway from ligand secretion to gene transcription: Molecular mechanisms and pharmacological targets

Baarsma, Hoeke A., Königshoff, Melanie, Gosens, Reinoud

Journal:

Pharmacology & Therapeutics

Year:

2013

Language:

english

File:

PDF, 774 KB

english, 2013

16

[American Thoracic Society American Thoracic Society 2009 International Conference, May 15-20, 2009 â¢ San Diego, California - ()] D17. FIBROBLASTS, PROGENITOR CELLS, AND MODELS OF INTERSTITIAL FIBROSIS THAT REVEAL MECHANISMS OF DISEASE - Dimethylarginine Dimethylaminohydrolase 2 in Idiopathic Pulmonary Fibrosis.

Pullamsetti, SS, Savai, R, Dumitrascu, R, Konigshoff, M, Ghofrani, HA, Weissmann, N, Grimminger, F, Eickelberg, O, Guenther, A, Leiper, J, Seeger, W, Schermuly, RT

Year:

2009

File:

PDF, 117 KB

2009

17

[American Thoracic Society American Thoracic Society 2009 International Conference, May 15-20, 2009 â¢ San Diego, California - ()] B60. PULMONARY FIBROSIS: THE FIBROBLAST - Dysregulation of the Wnt/beta-Catenin Pathway in Idiopathic Pulmonary Fibrosis: Epithelial-Derived Dickkopf Proteins Control Wnt-Induced Effects.

Konigshoff, M, Pfaff, EM, Balsara, N, Gunther, A, Eickelberg, O

Year:

2009

File:

PDF, 116 KB

2009

18

Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis

Sevdalina Nikolova, Andreas Guenther, Rajkumar Savai, Norbert Weissmann, Hossein A Ghofrani, Melanie Konigshoff, Oliver Eickelberg, Walter Klepetko, Robert Voswinckel, Werner Seeger, Friedrich Grimmin

Journal:

Respiratory Research

Year:

2010

Language:

english

File:

PDF, 3.63 MB

english, 2010

19

CARM1 Regulates Alveolar Epithelial Senescence and Elastase-induced Emphysema Susceptibility

Sarker, Rim S.J., John-Schuster, Gerrit, Bohla, Alexander, Mutze, Kathrin, Burgstaller, Gerald, Bedford, Mark T, Königshoff, Melanie, Eickelberg, Oliver, Yildirim, Ali Ö

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2015

Language:

english

File:

PDF, 1.54 MB

english, 2015

20

Breaking the In Vitro Barrier in Respiratory Medicine: Engineered Microphysiological Systems for COPD and Beyond

Benam, Kambez H, Königshoff, Melanie, Eickelberg, Oliver

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2017

Language:

english

File:

PDF, 737 KB

english, 2017

21

Plasminogen activator inhibitor type 1 inhibits smooth muscle cell proliferation in pulmonary arterial hypertension

Fotini M. Kouri, Markus A. Queisser, Melanie Königshoff, Izabella Chrobak, Klaus T. Preissner, Werner Seeger, Oliver Eickelberg

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2008

Language:

english

File:

PDF, 841 KB

english, 2008

22

From molecule to man: Integrating molecular biology with whole organ physiology in studying respiratory disease

Melanie Königshoff, Franziska Uhl, Reinoud Gosens

Journal:

Pulmonary Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 303 KB

english, 2011

23

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] D28. DEVELOPMENTAL SIGNALING REBORN IN ADULT LUNG DISEASE - Sonic Hedgehog Mediates Epithelial/Mesenchymal Crosstalk In Lung Cancer

Bermudez, Olga M., Koch, Ina, Hennen, Elisabeth, Stein, Maria M., Lindner, Michael, Konigshoff, Melanie, Eickelberg, Oliver

Year:

2012

Language:

english

File:

PDF, 19 KB

english, 2012

24

Hallmarks of the ageing lung

Meiners, S., Eickelberg, O., Konigshoff, M.

Journal:

European Respiratory Journal

Year:

2015

Language:

english

File:

PDF, 872 KB

english, 2015

25

S100a4 Is Secreted by Alternatively Activated Alveolar Macrophages and Promotes Activation of Lung Fibroblasts in Pulmonary Fibrosis

Zhang, Wei, Ohno, Shinji, Steer, Beatrix, Klee, Stephan, Staab-Weijnitz, Claudia A., Wagner, Darcy, Lehmann, Mareike, Stoeger, Tobias, Königshoff, Melanie, Adler, Heiko

Journal:

Frontiers in Immunology

Year:

2018

Language:

english

File:

PDF, 4.49 MB

english, 2018

26

Cell-specific expression of runt-related transcription factor 2 contributes to pulmonary fibrosis

Mümmler, Carlo, Burgy, Olivier, Hermann, Sarah, Mutze, Kathrin, Günther, Andreas, Königshoff, Melanie

Journal:

The FASEB Journal

Year:

2017

Language:

english

File:

PDF, 2.35 MB

english, 2017

27

Kurzlehrbuch Biochemie || 8 Hormone

Königshoff, Melanie, Brandenburger, Timo, Duszenko, Michael

Year:

2018

Language:

german

File:

PDF, 3.04 MB

german, 2018

28

Shared and distinct mechanisms of fibrosis

Distler, Jörg H. W., Györfi, Andrea-Hermina, Ramanujam, Meera, Whitfield, Michael L., Königshoff, Melanie, Lafyatis, Robert

Journal:

Nature Reviews Rheumatology (formerly Nature Clinical Practice Rheumatology)

Year:

2019

Language:

english

File:

PDF, 2.29 MB

english, 2019

29

Mating behaviour of the ‘cosmopolitan’ species Phyllognathopus viguieri (Copepoda: Harpacticoida) and its systematical significance

D. Königshoff, T. Glatzel

Journal:

Journal of Zoological Systematics and Evolutionary Research

Year:

2008

Language:

english

File:

PDF, 417 KB

english, 2008

30

Paired Immunoglobulin-Like Receptor–B Inhibits Pulmonary Fibrosis by Suppressing Profibrogenic Properties of Alveolar Macrophages

Karo-Atar, Danielle, Moshkovits, Itay, Eickelberg, Oliver, Königshoff, Melanie, Munitz, Ariel

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2013

Language:

english

File:

PDF, 1.29 MB

english, 2013

31

Preclinical validation and imaging of Wnt-induced repair in human 3D lung tissue cultures

Uhl, F. E., Vierkotten, S., Wagner, D. E., Burgstaller, G., Costa, R., Koch, I., Lindner, M., Meiners, S., Eickelberg, O., Konigshoff, M.

Journal:

European Respiratory Journal

Year:

2015

Language:

english

File:

PDF, 1.21 MB

english, 2015

32

Terguride ameliorates monocrotaline-induced pulmonary hypertension in rats

Dumitrascu, R., Kulcke, C., Konigshoff, M., Kouri, F., Yang, X., Morrell, N., Ghofrani, H. A., Weissmann, N., Reiter, R., Seeger, W., Grimminger, F., Eickelberg, O., Schermuly, R. T., Pullamsetti, S.

Journal:

European Respiratory Journal

Year:

2011

Language:

english

File:

PDF, 1.31 MB

english, 2011

33

The Angiotensin II Receptor 2 Is Expressed and Mediates Angiotensin II Signaling in Lung Fibrosis

Königshoff, Melanie, Wilhelm, Anke, Jahn, Andreas, Sedding, Daniel, Amarie, Oana Veronica, Eul, Bastian, Seeger, Werner, Fink, Ludger, Günther, Andreas, Eickelberg, Oliver, Rose, Frank

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2007

Language:

english

File:

PDF, 1.35 MB

english, 2007

34

Linking bronchopulmonary dysplasia to adult chronic lung diseases: role of WNT signaling

Ota, Chiharu, Baarsma, Hoeke A., Wagner, Darcy E., Hilgendorff, Anne, Königshoff, Melanie

Journal:

Molecular and Cellular Pediatrics

Year:

2016

Language:

english

File:

PDF, 1.07 MB

english, 2016

35

Lung volumes predict survival in patients with chronic lung allograft dysfunction

Kneidinger, Nikolaus, Milger, Katrin, Janitza, Silke, Ceelen, Felix, Leuschner, Gabriela, Dinkel, Julien, Königshoff, Melanie, Weig, Thomas, Schramm, René, Winter, Hauke, Behr, Jürgen, Neurohr, Claus

Journal:

European Respiratory Journal

Year:

2017

Language:

english

File:

PDF, 412 KB

english, 2017

36

Kurzlehrbuch Biochemie || 10 Stoffwechsel der einzelnen Organe

Königshoff, Melanie, Brandenburger, Timo, Duszenko, Michael

Year:

2018

Language:

german

File:

PDF, 4.27 MB

german, 2018

37

WNT/β-Catenin Signaling Induces IL-1β Expression by Alveolar Epithelial Cells in Pulmonary Fibrosis

Aumiller, Verena, Balsara, Nisha, Wilhelm, Jochen, Günther, Andreas, Königshoff, Melanie

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2013

Language:

english

File:

PDF, 2.02 MB

english, 2013

38

SNAI transcription factors mediate epithelial-mesenchymal transition in lung fibrosis

Jayachandran, A, Konigshoff, M, Yu, H, Rupniewska, E, Hecker, M, Klepetko, W, Seeger, W, Eickelberg, O

Journal:

Year:

2009

Language:

english

File:

PDF, 2.00 MB

english, 2009

39

In search of the fibrotic epithelial cell: opportunities for a collaborative network

Jenkins, G., Blanchard, A., Borok, Z., Bradding, P., Ehrhardt, C., Fisher, A., Hirani, N., Johnson, S., Konigshoff, M., Maher, T. M., Millar, A., Parfrey, H., Scotton, C., Tetley, T., Thickett, D., Wo

Journal:

Year:

2012

Language:

english

File:

PDF, 95 KB

english, 2012

40

Lung-selective gene responses to alveolar hypoxia: potential role for the bone morphogenetic antagonist gremlin in pulmonary hypertension

Costello, C. M., Howell, K., Cahill, E., McBryan, J., Konigshoff, M., Eickelberg, O., Gaine, S., Martin, F., McLoughlin, P.

Journal:

AJP Lung Cellular and Molecular Physiology

Year:

2008

Language:

english

File:

PDF, 1.13 MB

english, 2008

41

WNT Signaling in Lung Disease

Königshoff, Melanie, Eickelberg, Oliver

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2010

Language:

english

File:

PDF, 457 KB

english, 2010

42

The new Back to Basics section: emerging concepts in basic and translational medicine

Journal:

European Respiratory Journal

Year:

2014

Language:

english

File:

PDF, 272 KB

english, 2014

43

Loss of RAGE in Pulmonary Fibrosis

Queisser, Markus A., Kouri, Fotini M., Königshoff, Melanie, Wygrecka, Malgorzata, Schubert, Uwe, Eickelberg, Oliver, Preissner, Klaus T.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2008

Language:

english

File:

PDF, 917 KB

english, 2008

44

Cigarette smoke alters the secretome of lung epithelial cells

Mossina, Alessandra, Lukas, Christina, Merl-Pham, Juliane, Uhl, Franziska E., Mutze, Kathrin, Schamberger, Andrea, Staab-Weijnitz, Claudia, Jia, Jie, Yildirim, Ali Ö., Königshoff, Melanie, Hauck, Stef

Journal:

Year:

2016

Language:

english

File:

PDF, 943 KB

english, 2016

45

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] D28. DEVELOPMENTAL SIGNALING REBORN IN ADULT LUNG DISEASE - Activation Of Wnt/Beta-Catenin Signaling Promotes Lung Epithelial Repair In Emphysema

Callegari, Jens, Kipp, Julia, Konigshoff, Melanie

Year:

2012

Language:

english

File:

PDF, 19 KB

english, 2012

46

‘WNT-er is coming’ : WNT signalling in chronic lung diseases

Baarsma, H A, Königshoff, M

Journal:

Year:

2017

Language:

english

File:

PDF, 1.31 MB

english, 2017

47

Embedding of Precision-Cut Lung Slices in Engineered Hydrogel Biomaterials Supports Extended ex vivo Culture

Bailey, Kolene E., Pino, Christopher, Lennon, Mallory L, Lyons, Anne, Jacot, Jeffrey G, Lammers, Steven R, Königshoff, Melanie, Magin, Chelsea M

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2019

Language:

english

File:

PDF, 1.11 MB

english, 2019

48

Human lung stem cells: Oh, the places you'll go!

Melanie Königshoff, Johannes Schwarz, Oliver Eickelberg

Journal:

EMBO Molecular Medicine

Year:

2011

Language:

english

File:

PDF, 259 KB

english, 2011

49

Transgelin is a direct target of TGF- /Smad3-dependent epithelial cell migration in lung fibrosis

Yu, H., Konigshoff, M., Jayachandran, A., Handley, D., Seeger, W., Kaminski, N., Eickelberg, O.

Journal:

The FASEB Journal

Year:

2008

Language:

english

File:

PDF, 968 KB

english, 2008

50

Role of von Hippel-Lindau protein in fibroblast proliferation and fibrosis

Zhou, Q., Pardo, A., Konigshoff, M., Eickelberg, O., Budinger, G. R. S., Thavarajah, K., Gottardi, C. J., Jones, J., Varga, J., Selman, M., Sznajder, J. I., Raj, J. U., Zhou, G.

Journal:

The FASEB Journal

Year:

2011

Language:

english

File:

PDF, 1.20 MB

english, 2011

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